Blister pack with tablets in technology IOC - blistering process

A compendium of knowledge on blistering, blisters and blister packs in the context of pharmaceuticals, dietary supplements and medical foods

1. Definition and role of blistering

Blistering is a technology for individually packaging tablets and capsules, aimed at ensuring maximum freshness and protection of the product. This system improves dosing, guarantees hygiene and meets rigorous quality standards.

  • Security: Prevents the negative effects of moisture, oxygen and light.
  • Practicality: Enables quick recognition of the number of doses and facilitates control.
  • Compatibility: Meets GMP requirements and pharmacopoeial standards.

2. A Brief History and Evolution of Blister Packs

  • 1960: The beginnings – introduction of mass PVC packaging.
  • 70/80 – XNUMX/XNUMX: Barrier-enhancing laminates are becoming the standard.
  • End of the 20th century: Cold forming and tightening of quality standards.
  • 21st century: Research on biodegradable materials and intelligent packaging systems.

3. Blister technologies

Thermoforming

The foil (e.g. PVC, PET) is heated to a plastic state and formed into pockets, then bonded to the protective layer – a quick and effective solution.

Cold forming

Mechanical embossing of multi-layer foil (often with the addition of aluminium) creates exceptionally barrier packaging, ideal for highly sensitive products.

4. Materials used in blisters

  • Plastics: PVC, PVDC, PCTFE, PET – selected to provide appropriate barrier and aesthetics.
  • Aluminum foils and laminates: They provide excellent protection against environmental factors.
  • Biodegradable materials: Forward-looking solutions that, despite the challenges, represent the future of ecological packaging.

5. Key regulatory requirements

  • GMP: Essential control of production processes.
  • Pharmacopoeial and ISO standards: Tightness, stability and material migration tests.
  • Safe work: Special packaging to protect against unauthorized opening.

6. Product stability and safety

  • Protection of active substances: Minimizing degradation caused by moisture, oxygen or UV radiation.
  • Mechanical resistance: Reducing the risk of damage during transport and use.

7. Specifics of supplements and medical food

  • Lower regulatory requirements compared to pharmaceuticals, but rising quality standards.
  • Variety of forms – from capsules and tablets to sachets and powders.
  • Stability of active ingredients and attractive product presentation are priorities.

8. Quality control and process validation

  • Leak tests: Immersion, helium or bomb methods check the integrity of the package.
  • Stability studies: Controls under various temperature and humidity conditions.
  • Migration assessment: Ensuring that no harmful substances pass into the product.

9. Economy and ecology in blistering

  • Cost optimization: The choice of materials depends on your budget and the level of protection required.
  • Automation: Modern production lines increase efficiency at large scale.
  • Recycling and Sustainability: Separating materials is a challenge, but increasingly better ecological solutions are being developed.

10. Modern trends and innovations

  • Smart packaging: Built-in sensors monitoring conditions (humidity, oxygen) ensure real-time quality control.
  • Active packaging: Absorption layers that reduce moisture and oxygen levels.
  • 3D printing: Personalized and non-standard packaging, allowing for innovative visual and functional solutions.
  • Digital integration: Packaging supporting therapy management thanks to NFC or RFID – dosing suggestions for patients.

11. Summary

The key advantages of blistering are a high level of protection and ease of use while meeting strict quality standards. Precise selection of technology and materials allows for extending the durability of products, and innovative solutions prepare the ground for future, intelligent packaging systems.

  • Protection and stability – protection against environmental influences.
  • Efektywność operacyjna – easy dose control and high efficiency production of dietary supplements.
  • Innovation – development of intelligent and ecological packaging.

FAQ: Blistering and blister pack

What exactly is blistering?

The process of individually packaging doses of a medicine or supplement that ensures high hygiene, precise dosing and long-lasting freshness.

What are the features of a blister?

A blister is a ready-made, formed pocket made of foil or laminate, designed to protect the contents from external factors and facilitate dispensing.

Why is blistering so important?

It ensures that medical products and supplements remain stable, are protected from degradation and offer intuitive operation – the key to user safety and satisfaction.

Close-up of a blister filled with capsules - high quality blistering
See how blister packs provide protection against moisture and light, and improve the safety of supplements and medical foods.

A Global Approach to Marketing Blister Packaging Services

In pharmacy, the main focus is on safety, compliance with standards and proven experience. Messages emphasize the status of the leader ("world leading", "trusted partner") and regulatory expertise, which builds trust with recipients.

In the dietary supplement sector, marketing language focuses on consumer convenience and visual appeal of packaging. Key issues are ease of dosing, product durability and aesthetics, or so-called "shelf appeal", thanks to which the brand stands out on the market.

In the medical food niche, pharmaceutical approaches are combined with nutritional elements. The message focuses on precise dosing, maintaining nutritional value and intuitive use - all while maintaining the highest quality standards.

Blistering with International Organic Company

International Organic Company is a partner that combines pharmaceutical precision with organic purity. Our comprehensive blistering services provide:

  • Reliability and Compliance: Working according to GMP and international standards guarantees the full safety of your product.
  • Specialization for organic products: Certified materials, free from undesirable substances, emphasize the natural character of the product.
  • Stability and precise dosing: Modern technologies ensure airtightness and protection against external factors, with security options (child-proof) for additional comfort.
  • Attractive design: The aesthetics of the packaging support brand recognition and distinguish the product on the store shelf.
  • Flexibility and comprehensiveness: Short lead times, full traceability (serialization, QR codes) and expert support at every stage of the project.

choosing International Organic Company, you invest in packaging that protects what is most valuable and highlights the high quality of your product. Contact us to see how we can strengthen the value of your brand.

Blister with probiotic capsules - an example of professional packaging
See how proper blistering can extend the life of probiotic bacteria and ensure the highest quality of dietary supplements.

IOC has been offering packaging and blistering services for over 15 years. Find out more. Contact us!

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